Proximal bicarbonate reabsorption during Ringer and albumin infusions in the rat.
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چکیده
منابع مشابه
Proximal tubular bicarbonate reabsorption and PCO2 in chronic metabolic alkalosis in the rat.
Studies were undertaken to define the pattern of proximal tubular bicarbonate reabsorption and its relation to tubular and capillary PCO2 in rats with chronic metabolic alkalosis (CMA). CMA was induced by administering furosemide to rats ingesting a low electrolyte diet supplemented with NaHCO3 and KHCO3. Proximal tubular bicarbonate reabsorption and PCO2 were measured in CMA rats either 4-7 or...
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In the intact rat kidney, bicarbonate reabsorption in the early proximal tubule (EP) is strongly dependent on delivery. Independent of delivery, metabolic acidosis stimulates EP bicarbonate reabsorption. In this study, we investigated whether systemic pH changes induced by acute or chronic respiratory acid-base disorders also affect EP HCO3- reabsorption, independent of delivery (FLHCO3, filter...
متن کاملControl of proximal bicarbonate reabsorption in normal and acidotic rats.
This free-flow micropuncture study examined the dependence of bicarbonate reabsorption in the rat superficial proximal convoluted tubule to changes in filtered bicarbonate load, and thereby the contribution of the proximal tubule to the whole kidney's response to such changes. The independent effects of extracellular fluid (ECF) volume expansion and of acidosis on proximal bicarbonate reabsorpt...
متن کاملInhibition of bicarbonate reabsorption in the rat proximal tubule by activation of luminal P2Y1 receptors.
The present study used a stationary microperfusion technique to investigate in vivo the effect of P2Y1 receptor activation on bicarbonate reabsorption in the rat proximal tubule. Proximal tubules were perfused with a bicarbonate Ringer solution before flow was stopped by means of an oil block. The recovery of lumen pH from the initial value (pH 8.0) to stationary values (pH approximately 6.7) w...
متن کاملKinetic study of bicarbonate reabsorption in proximal tubule of the rat.
MALNIC, GERHARD, AND MARGARIDA DE MELLO-AIRES. Kinetic study of bicarbonate reabsorption in proximal tubule of the rat. Am. J. Physiol. 220(6) : 1759-1767. 197 1 .-Continuous recording of tubular pH was performed during stopped-flow microperfusion of rat proximal tubules with isotonic solutions containing 25 or 100 mEq/liter HCO 3, by means of an antimony microelectrode. After stabilization of ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1976
ISSN: 0021-9738
DOI: 10.1172/jci108419